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1

Gene Network Analysis during Early Infection of Human Coronary Artery Smooth Muscle Cells by Trypanosoma cruzi and Its gp83 Ligand

Pius N. Nde, Candice A. Johnson, Siddharth Pratap, Tatiana C. Cardenas, Yuliya Y. Kleshchenko, Vyacheslav A. Furtak, Kaneatra J. Simmons, Maria F. Lima, Fernando Villalta

Journal:

Chemistry & Biodiversity

Year:

2010

Language:

english

File:

PDF, 1.72 MB

english, 2010

2

Sterol 14α-Demethylase as a Potential Target for Antitrypanosomal Therapy: Enzyme Inhibition and Parasite Cell Growth

Galina I. Lepesheva, Robert D. Ott, Tatiana Y. Hargrove, Yuliya Y. Kleshchenko, Inge Schuster, W. David Nes, George C. Hill, Fernando Villalta, Michael R. Waterman

Journal:

Chemistry & Biology

Year:

2007

Language:

english

File:

PDF, 1.14 MB

english, 2007

3

Perspectives on theTrypanosoma cruzi–host cell receptor interactions

Fernando Villalta, Julio Scharfstein, Anthony W. Ashton, Kevin M. Tyler, Fangxia Guan, Shankar Mukherjee, Maria F. Lima, Sandra Alvarez, Louis M. Weiss, Huan Huang, Fabiana S. Machado, Herbert B. Tano

Journal:

Parasitology Research

Year:

2009

Language:

english

File:

PDF, 211 KB

english, 2009

4

CYP51: A Major Drug Target in the Cytochrome P450 Superfamily

Galina I. Lepesheva, Tatyana Y. Hargrove, Yuliya Kleshchenko, W. David Nes, Fernando Villalta, Michael R. Waterman

Journal:

Year:

2008

Language:

english

File:

PDF, 506 KB

english, 2008

5

Growth of Isolated Amastigotes of Trypanosoma cruzi in Cell-Free Medium

FERNANDO VILLALTA, FELIPE KIERSZENBAUM

Journal:

Journal of Eukaryotic Microbiology

Year:

1982

Language:

english

File:

PDF, 3.01 MB

english, 1982

6

Cross-reactivity of Vector-borne Metacyclic Forms of Trypanosoma cruzi with Mammalian and Culture Stages

FERNANDO VILLALTA, FELIPE KIERSZENBAUM

Journal:

Journal of Eukaryotic Microbiology

Year:

1983

Language:

english

File:

PDF, 395 KB

english, 1983

7

Extracellular Killing of Trypanosoma cruzi Amastigotes by Human Eosinophils

FERNANDO VILLALTA, H. STUART PANKRATZ, FELIPE KIERSZENBAUM

Journal:

Journal of Eukaryotic Microbiology

Year:

1987

Language:

english

File:

PDF, 3.91 MB

english, 1987

8

Epidermal Growth Factor Binds to a Receptor on Trypanosoma cruziAmastigotes Inducing Signal Transduction Events and Cell Proliferation

TOMAR J. GHANSAH, EDWARD C. AGER, PHYLLIS FREEMAN-JUNIOR, FERNANDO VILLALTA, MARIA F. LIMA

Journal:

Journal of Eukaryotic Microbiology

Year:

2002

Language:

english

File:

PDF, 882 KB

english, 2002

9

Enhanced Multiplication of Intracellular (Amastigote) Stages of Trypanosoma cruzi In Vitro

FERNANDO VILLALTA, FELIPE KIERSZENBAUM

Journal:

Journal of Eukaryotic Microbiology

Year:

1984

Language:

english

File:

PDF, 309 KB

english, 1984

10

The effect of swainsonine on the association of Trypanosoma cruzi with host cells

Fernando Villalta, Felipe Kierszenbaum

Journal:

Molecular and Biochemical Parasitology

Year:

1985

Language:

english

File:

PDF, 531 KB

english, 1985

11

Role of membrane N-linked oligosaccharides in host cell interaction with invasive forms of Trypanosoma cruzi

Fernando Villalta, Felipe Kierszenbaum

Journal:

Molecular and Biochemical Parasitology

Year:

1987

Language:

english

File:

PDF, 490 KB

english, 1987

12

Trypanosoma cruzi trypomastigote clones differentially express a parasite cell adhesion molecule

Maria F. Lima, Fernando Villalta

Journal:

Molecular and Biochemical Parasitology

Year:

1989

Language:

english

File:

PDF, 853 KB

english, 1989

13

Trypanosoma cruzi receptors for human transferrin and their role

Maria F. Lima, Fernando Villalta

Journal:

Molecular and Biochemical Parasitology

Year:

1990

Language:

english

File:

PDF, 664 KB

english, 1990

14

Purification of a 74-kilodalton surface glycoprotein from heart myoblasts that inhibits binding and entry of Trypanosoma cruzi into heart cells

Fernando Villalta, Antonio Ruiz-Ruano, Anthony A. Valentine, Maria F. Lima

Journal:

Molecular and Biochemical Parasitology

Year:

1993

Language:

english

File:

PDF, 1.62 MB

english, 1993

15

Signal Transduction in Human Macrophages by gp83 Ligand ofTrypanosoma cruzi:Trypomastigote gp83 Ligand Up-Regulates Trypanosome Entry through the MAP Kinase Pathway

Fernando Villalta, Yuan Zhang, Kartz E. Bibb, James M. Burns Jr., Maria F. Lima

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 701 KB

english, 1998

16

Trypanosoma cruzi Uses a 45-kDa Mucin for Adhesion to Mammalian Cells

Corey W. Turner, Maria F. Lima, Fernando Villalta

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 137 KB

english, 2002

17

Signal Transduction in Human Macrophages by gp83 Ligand of Trypanosoma cruzi: Trypomastigote gp83 Ligand Up-Regulates Trypanosome Entry through Protein Kinase C Activation

Fernando Villalta, Yuan Zhang, Kartz E. Bibb, Siddharth Pratap, James M. Burns Jr., Maria F. Lima

Journal:

Molecular Cell Biology Research Communications

Year:

1999

Language:

english

File:

PDF, 115 KB

english, 1999

18

Role of cell surface mannose residues in host cell invasion by Trypanosoma cruzi

Fernando Villalta, Felipe Kierszenbaum

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1983

Language:

english

File:

PDF, 493 KB

english, 1983

19

Host-cell invasion by Trypanosoma cruzi: Role of cell surface galactose residues

Fernando Villalta, Felipe Kierszenbaum

Journal:

Biochemical and Biophysical Research Communications

Year:

1984

Language:

english

File:

PDF, 509 KB

english, 1984

20

Purification of Trypanosoma cruzi surface proteins involved in adhesion to host cells

Fernando Villalta, Maria F. Lima, Lin Zhou

Journal:

Biochemical and Biophysical Research Communications

Year:

1990

Language:

english

File:

PDF, 513 KB

english, 1990

21

Mechanism of nifurtimox toxicity in different forms of Trypanosoma cruzi

Roberto Docampo, Silvia N.J. Moreno, Andrés O.M. Stoppani, Wilson Leon, Fernando S. Cruz, Fernando Villalta, Ramiro F.A. Muniz

Journal:

Biochemical Pharmacology

Year:

1981

Language:

english

File:

PDF, 496 KB

english, 1981

22

Stable RNA interference of host thrombospondin-1 blocks Trypanosoma cruzi infection

Kaneatra J. Simmons, Pius N. Nde, Yuliya Y. Kleshchenko, Maria F. Lima, Fernando Villalta

Journal:

Year:

2006

Language:

english

File:

PDF, 202 KB

english, 2006

23

Attachment of Trypanosoma cruzi to host cells: A monoclonal antibody recognizes a trypomastigote stage-specific epitope on the gp 83 required for parasite attachment

Fernando Villalta, Maria F. Lima, Antonio Ruiz-Ruano, Lin Zhou

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 1.13 MB

english, 1992

24

Host-cell attachment by Trypanosoma cruzi: Identification of an adhesion molecule

Maria F. Lima, Fernando Villalta

Journal:

Biochemical and Biophysical Research Communications

Year:

1988

Language:

english

File:

PDF, 473 KB

english, 1988

25

Novel mechanism that Trypanosoma cruzi uses to adhere to the extracellular matrix mediated by human galectin-3

Tapria N. Moody, Josiah Ochieng, Fernando Villalta

Journal:

Year:

2000

Language:

english

File:

PDF, 176 KB

english, 2000

26

A ligand that Trypanosoma cruzi uses to bind to mammalian cells to initiate infection

Fernando Villalta, Cassandra M Smith, Antonio Ruiz-Ruano, Maria F Lima

Journal:

Year:

2001

Language:

english

File:

PDF, 331 KB

english, 2001

27

Organocatalytic, Enantioselective Synthesis of VNI: A Robust Therapeutic Development Platform for Chagas, a Neglected Tropical Disease

Dobish, Mark C., Villalta, Fernando, Waterman, Michael R., Lepesheva, Galina I., Johnston, Jeffrey N.

Journal:

Organic Letters

Year:

2012

Language:

english

File:

PDF, 503 KB

english, 2012

28

Fab' Fragments of a mAb to a Member of Family 2 of Trans-sialidases of Trypanosoma cruzi Block Trypanosome Invasion of Host Cells and Neutralize Infection by Passive Immunization

FERNANDO VILLALTA, CASSANDRA M. SMITH, JAMES M. BURNS JR., GAUTAM CHAUDHURI, MARIA F. LIMA

Journal:

Annals of the New York Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 196 KB

english, 1996

29

Indomethacin Amides as a Novel Molecular Scaffold for Targeting Trypanosoma cruzi Sterol 14α-Demethylase

Konkle, Mary E., Hargrove, Tatiana Y., Kleshchenko, Yuliya Y., von Kries, Jens P., Ridenour, Whitney, Uddin, Md. Jashim, Caprioli, Richard M., Marnett, Lawrence J., Nes, W. David, Villalta, Fernando,

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 335 KB

english, 2009

30

Cocaine Enhances HIV-1–Induced CD4+ T-Cell Apoptosis

Pandhare, Jui, Addai, Amma B., Mantri, Chinmay K., Hager, Cynthia, Smith, Rita M., Barnett, Louis, Villalta, Fernando, Kalams, Spyros A., Dash, Chandravanu

Journal:

The American Journal of Pathology

Year:

2014

Language:

english

File:

PDF, 1.50 MB

english, 2014

31

Role of surface N-acetylglucosamine residues on host cell infection by Trypanosoma cruzi

Villalta, Fernando, Kierszenbaum, Felipe

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

1985

Language:

english

File:

PDF, 533 KB

english, 1985

32

Structural Basis for Rational Design of Inhibitors Targeting Trypanosoma cruzi Sterol 14α-Demethylase: Two Regions of the Enzyme Molecule Potentiate Its Inhibition

Friggeri, Laura, Hargrove, Tatiana Y., Rachakonda, Girish, Williams, Amanda D., Wawrzak, Zdzislaw, Di Santo, Roberto, De Vita, Daniela, Waterman, Michael R., Tortorella, Silvano, Villalta, Fernando, L

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 7.46 MB

english, 2014

33

Discovery of an ergosterol-signaling factor that regulates Trypanosoma brucei growth

Haubrich, Brad A., Singha, Ujjal K., Miller, Matthew B., Nes, Craigen R., Anyatonwu, Hosanna, Lecordier, Laurence, Patkar, Presheet, Leaver, David J., Villalta, Fernando, Vanhollebeke, Benoit, Chaudhu

Journal:

The Journal of Lipid Research

Year:

2015

Language:

english

File:

PDF, 1.24 MB

english, 2015

34

Regulation and use of the extracellular matrix by Trypanosoma cruzi during early infection

Nde, Pius N., Lima, Maria F., Johnson, Candice A., Pratap, Siddharth, Villalta, Fernando

Journal:

Frontiers in Immunology

Year:

2012

Language:

english

File:

PDF, 862 KB

english, 2012

35

Novel sterol metabolic network of Trypanosoma brucei procyclic and bloodstream forms

Nes, Craigen R., Singha, Ujjal K., Liu, Jialin, Ganapathy, Kulothungan, Villalta, Fernando, Waterman, Michael R., Lepesheva, Galina I., Chaudhuri, Minu, Nes, W. David

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 1.31 MB

english, 2012

36

Immunization with Hexon Modified Adenoviral Vectors Integrated with gp83 Epitope Provides Protection against Trypanosoma cruzi Infection

Farrow, Anitra L., Rachakonda, Girish, Gu, Linlin, Krendelchtchikova, Valentina, Nde, Pius N., Pratap, Siddharth, Lima, Maria F., Villalta, Fernando, Matthews, Qiana L., Rodrigues, Mauricio Martins

Journal:

PLoS Neglected Tropical Diseases

Year:

2014

Language:

english

File:

PDF, 2.38 MB

english, 2014

37

A Novel Role of Proline Oxidase in HIV-1 Envelope Glycoprotein-induced Neuronal Autophagy

Pandhare, Jui, Dash, Sabyasachi, Jones, Bobby, Villalta, Fernando, Dash, Chandravanu

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 1.92 MB

english, 2015

38

Antiparasitic effect in vitro , activity in a murine model of Chagas disease, and structural characterization in complex with the target enzyme CYP51 from Trypanosoma cruzi of the potent clinical candidate VT-1161

Hoekstra, William J., Hargrove, Tatiana Y., Wawrzak, Zdzislaw, Batista, Denis D.G., da Silva, Cristiane F., Nefertiti, Aline S. G., Rachakonda, Girish, Schotzinger, Robert J., Villalta, Fernando, Soei

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 6.27 MB

english, 2015

39

Social coercion of larval development in an ant species

Villalta, Irene, Amor, Fernando, Cerdá, Xim, Boulay, Raphaël

Journal:

Naturwissenschaften (The Science of Nature)

Year:

2016

Language:

english

File:

PDF, 1013 KB

english, 2016

40

Filamin A Is Involved in HIV-1 Vpu-mediated Evasion of Host Restriction by Modulating Tetherin Expression

Dotson, Dominique, Woodruff, Elvin A., Villalta, Fernando, Dong, Xinhong

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 2.57 MB

english, 2016

41

Concanavalin a Binding Receptors on Trypanosoma cruzi Amastigotes

Fernando Villalta, Alejandro M. Katzin, Wilson Leon and Stella Gonzales-Cappa

Journal:

Journal of Parasitology

Year:

1980

Language:

english

File:

PDF, 349 KB

english, 1980

42

Effect of Purification by DEAE-Cellulose Column on Infectivity of Trypanosoma cruzi Blood Forms

Fernando V. Villalta and Wilson Leon

Journal:

Journal of Parasitology

Year:

1979

Language:

english

File:

PDF, 224 KB

english, 1979

43

Nutritional versus genetic correlates of caste differentiation in a desert ant

AMOR, FERNANDO, VILLALTA, IRENE, DOUMS, CLAUDIE, ANGULO, ELENA, CAUT, STEPHANE, CASTRO, SARA, CERDÁ, XIM, BOULAY, RAPHAËL

Journal:

Ecological Entomology

Year:

2016

Language:

english

File:

PDF, 600 KB

english, 2016

44

interactions

Villalta, Fernando, Scharfstein, Julio, Ashton, Anthony W, Tyler, Kevin M

Year:

2010

Language:

english

File:

PDF, 77 KB

english, 2010

45

Crystal structure of the new investigational drug candidate VT-1598 in complex with Aspergillus fumigatus sterol 14α-demethylase provides insights into its broad-spectrum antifungal activity.

Hargrove, Tatiana Y., Garvey, Edward P., Hoekstra, William J., Yates, Christopher M., Wawrzak, Zdzislaw, Rachakonda, Girish, Villalta, Fernando, Lepesheva, Galina. I.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2017

Language:

english

File:

PDF, 1.12 MB

english, 2017

46

Impact of residual pulmonary obstruction on the long-term outcome of patients with pulmonary embolism

Pesavento, Raffaele, Filippi, Lucia, Palla, Antonio, Visonà, Adriana, Bova, Carlo, Marzolo, Marco, Porro, Fernando, Villalta, Sabina, Ciammaichella, Maurizio, Bucherini, Eugenio, Nante, Giovanni, Batt

Journal:

European Respiratory Journal

Year:

2017

File:

PDF, 397 KB

2017

47

Origin and distribution of desert ants across the Gibraltar Straits

Villalta, Irene, Amor, Fernando, Galarza, Juan A., Dupont, Simon, Ortega, Patrocinio, Hefetz, Abraham, Dahbi, Abdallah, Cerdá, Xim, Boulay, Raphaël

Journal:

Molecular Phylogenetics and Evolution

Year:

2017

Language:

english

File:

PDF, 1.12 MB

english, 2017

48

Sterol 14α-Demethylase Structure-Based Design of VNI ((R)-N-(1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethyl)-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide)) Derivatives to Target Fungal Infections: Synthesis, Biological Evaluation, and Crystallographic Analysis

Friggeri, Laura, Hargrove, Tatiana Y, Wawrzak, Zdzislaw, Blobaum, Anna L., Rachakonda, Girish, Lindsley, Craig W, Villalta, Fernando, Nes, W. David, Botta, Maurizio, Guengerich, F. Peter, Lepesheva, G

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.06 MB

english, 2018

49

Thrombospondin-1 Interacts with Trypanosoma cruzi Surface Calreticulin to Enhance Cellular Infection

Johnson, Candice A., Kleshchenko, Yulia Y., Ikejiani, Adaeze O., Udoko, Aniekanabasi N., Cardenas, Tatiana C., Pratap, Siddharth, Duquette, Mark A., Lima, Maria F., Lawler, Jack, Villalta, Fernando, N

Journal:

Year:

2012

Language:

english

File:

PDF, 639 KB

english, 2012

50

Impact of cocaine abuse on HIV pathogenesis

Dash, Sabyasachi, Balasubramaniam, Muthukumar, Villalta, Fernando, Dash, Chandravanu, Pandhare, Jui

Journal:

Frontiers in Microbiology

Year:

2015

Language:

english

File:

PDF, 2.79 MB

english, 2015